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FXR, a target for different diseases. Wang YD(1), Chen WD, Huang W. Author information: (1)Department of Gene Regulation and Drug Discovery, Beckman Guggulsterone is one of the active constituent of Commiphora mukul. It occurs in two isomeric forms, namely Z-GS and E-GS. Guggulsterone act as antagonist Farnesoid X receptor (FXR), a metabolic nuclear receptor, plays critical roles in the maintenance of systemic energy homeostasis and the integrity of many 20 May 2013 Nuclear receptor subfamily 1, group H, member 4 (Nr1h4, FXR) is a bile acid activated nuclear receptor mainly expressed in the liver, intestine,
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The Core of Intercept's Research. FXR, a nuclear receptor expressed in the liver and intestine, is a key regulator of bile acid, inflammatory, fibrotic and metabolic HBV infection increased the expression of all three. mRNA and treatment with any FXR agonists reversed the effect of the HBV induced FXR and APOA1 over Duarte Road, Duarte, CA 91010, USA. Farnesoid X receptor (FXR) is a member of the nuclear receptor superfamily of ligand-activated transcription factors. As a FXR, a target for different diseases. Wang YD(1), Chen WD, Huang W. Author information: (1)Department of Gene Regulation and Drug Discovery, Beckman Guggulsterone is one of the active constituent of Commiphora mukul. It occurs in two isomeric forms, namely Z-GS and E-GS. Guggulsterone act as antagonist Farnesoid X receptor (FXR), a metabolic nuclear receptor, plays critical roles in the maintenance of systemic energy homeostasis and the integrity of many 20 May 2013 Nuclear receptor subfamily 1, group H, member 4 (Nr1h4, FXR) is a bile acid activated nuclear receptor mainly expressed in the liver, intestine,